MEIS1 regulates an HLF–oxidative stress axis in MLL-fusion gene leukemia

Leukemias with MLL translocations are often found in infants and are associated with poor outcomes. The pathogenesis of MLL-fusion leukemias has been linked to upregulation of HOX/MEIS1 genes. The functions of the Hox/Meis1 complex in leukemia, however, remain elusive. Here, we used inducible Meis1-...

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Dettagli Bibliografici
Pubblicato in:Blood
Autori principali: Roychoudhury, Jayeeta, Clark, Jason P., Gracia-Maldonado, Gabriel, Unnisa, Zeenath, Wunderlich, Mark, Link, Kevin A., Dasgupta, Nupur, Aronow, Bruce, Huang, Gang, Mulloy, James C., Kumar, Ashish R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2015
Soggetti:
Myeloid Neoplasia
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4400291/
https://ncbi.nlm.nih.gov/pubmed/25740828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-09-599258
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