Dynamic Modulation of Thymidylate Synthase Gene Expression and Fluorouracil Sensitivity in Human Colorectal Cancer Cells

Biomarkers have revolutionized cancer chemotherapy. However, many biomarker candidates are still in debate. In addition to clinical studies, a priori experimental approaches are needed. Thymidylate synthase (TS) expression is a long-standing candidate as a biomarker for 5-fluorouracil (5-FU) treatme...

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Vydáno v:PLoS One
Hlavní autoři: Wakasa, Kentaro, Kawabata, Rumi, Nakao, Seiki, Hattori, Hiroyoshi, Taguchi, Kenichi, Uchida, Junji, Yamanaka, Takeharu, Maehara, Yoshihiko, Fukushima, Masakazu, Oda, Shinya
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4400010/
https://ncbi.nlm.nih.gov/pubmed/25881233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123076
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