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Probing the Run-On Oligomer of Activated SgrAI Bound to DNA

SgrAI is a type II restriction endonuclease with an unusual mechanism of activation involving run-on oligomerization. The run-on oligomer is formed from complexes of SgrAI bound to DNA containing its 8 bp primary recognition sequence (uncleaved or cleaved), and also binds (and thereby activates for...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Shah, Santosh, Sanchez, Jonathan, Stewart, Andrew, Piperakis, Michael M., Cosstick, Richard, Nichols, Claire, Park, Chad K., Ma, Xin, Wysocki, Vicki, Bitinaite, Jurate, Horton, Nancy C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399878/
https://ncbi.nlm.nih.gov/pubmed/25880668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124783
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