Conditional Expression of Pomc in the Lepr-Positive Subpopulation of POMC Neurons Is Sufficient for Normal Energy Homeostasis and Metabolism

Peptides derived from the proopiomelanocortin (POMC) precursor are critical for the normal regulation of many physiological parameters, and POMC deficiency results in severe obesity and metabolic dysfunction. Conversely, augmentation of central nervous system melanocortin function is a promising the...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Lam, Daniel D., Attard, Courtney A., Mercer, Aaron J., Myers, Martin G., Rubinstein, Marcelo, Low, Malcolm J.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2015
Assuntos:
Energy Balance-Obesity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399319/
https://ncbi.nlm.nih.gov/pubmed/25594696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1373
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