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Conditional Expression of Pomc in the Lepr-Positive Subpopulation of POMC Neurons Is Sufficient for Normal Energy Homeostasis and Metabolism
Peptides derived from the proopiomelanocortin (POMC) precursor are critical for the normal regulation of many physiological parameters, and POMC deficiency results in severe obesity and metabolic dysfunction. Conversely, augmentation of central nervous system melanocortin function is a promising the...
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| Izdano u: | Endocrinology |
|---|---|
| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Endocrine Society
2015
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4399319/ https://ncbi.nlm.nih.gov/pubmed/25594696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1373 |
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