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Temporal changes in nutritional state affect hypothalamic POMC peptide levels independently of leptin in adult male mice

Hypothalamic proopiomelanocortin (POMC) neurons constitute a critical anorexigenic node in the central nervous system (CNS) for maintaining energy balance. These neurons directly affect energy expenditure and feeding behavior by releasing bioactive neuropeptides but are also subject to signals direc...

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Autors principals: Mercer, Aaron J., Stuart, Ronald C., Attard, Courtney A., Otero-Corchon, Veronica, Nillni, Eduardo A., Low, Malcolm J.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989737/
https://ncbi.nlm.nih.gov/pubmed/24518677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00540.2013
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