تحميل...
Biochemical, biological and structural properties of romidepsin (FK228) and its analogs as novel HDAC/PI3K dual inhibitors
Romidepsin (FK228, depsipeptide) is a potent histone deacetylase (HDAC) inhibitor that has FDA approval for the treatment of cutaneous and peripheral T-cell lymphomas. We have previously reported that FK228 and its analogs have an additional activity as phosphatidylinositol 3-kinase (PI3K) inhibitor...
محفوظ في:
| الحاوية / القاعدة: | Cancer Sci |
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| المؤلفون الرئيسيون: | , , , , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
BlackWell Publishing Ltd
2015
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4399029/ https://ncbi.nlm.nih.gov/pubmed/25492515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12585 |
| الوسوم: |
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