Role of VGF-Derived Carboxy-Terminal Peptides in Energy Balance and Reproduction: Analysis of “Humanized” Knockin Mice Expressing Full-Length or Truncated VGF

Targeted deletion of VGF, a secreted neuronal and endocrine peptide precursor, produces lean, hypermetabolic, and infertile mice that are resistant to diet-, lesion-, and genetically-induced obesity and diabetes. Previous studies suggest that VGF controls energy expenditure (EE), fat storage, and li...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Sadahiro, Masato, Erickson, Connor, Lin, Wei-Jye, Shin, Andrew C., Razzoli, Maria, Jiang, Cheng, Fargali, Samira, Gurney, Allison, Kelley, Kevin A., Buettner, Christoph, Bartolomucci, Alessandro, Salton, Stephen R.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398760/
https://ncbi.nlm.nih.gov/pubmed/25675362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1826
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