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Analysis of knockout mice suggests a role for VGF in the control of fat storage and energy expenditure

BACKGROUND: Previous studies of mixed background mice have demonstrated that targeted deletion of Vgf produces a lean, hypermetabolic mouse that is resistant to diet-, lesion-, and genetically-induced obesity. To investigate potential mechanism(s) and site(s) of action of VGF, a neuronal and endocri...

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Main Authors: Watson, Elizabeth, Fargali, Samira, Okamoto, Haruka, Sadahiro, Masato, Gordon, Ronald E, Chakraborty, Tandra, Sleeman, Mark W, Salton, Stephen R
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774661/
https://ncbi.nlm.nih.gov/pubmed/19863797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6793-9-19
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