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Germline Ablation of VGF Increases Lipolysis in White Adipose Tissue

Targeted deletion of VGF, a neuronal and endocrine secreted protein and neuropeptide precursor, produces a lean, hypermetabolic mouse that is resistant to diet-, lesion-, and genetically-induced obesity and diabetes. We hypothesized that increased sympathetic nervous system activity in Vgf−/Vgf− kno...

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Détails bibliographiques
Auteurs principaux: Fargali, Samira, Scherer, Thomas, Shin, Andrew C., Sadahiro, Masato, Buettner, Christoph, Salton, Stephen R.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488863/
https://ncbi.nlm.nih.gov/pubmed/22942234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-12-0172
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