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The prohormone VGF regulates β-cell function via insulin secretory granule biogenesis

The prohormone VGF is expressed in neuroendocrine and endocrine tissues and regulates nutrient and energy status both centrally and peripherally. We and others have shown that VGF-derived peptides have direct action on the islet β-cell as secretagogues and cytoprotective agents; however the endogeno...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Stephens, Samuel B., Edwards, Robert J., Sadahiro, Masato, Lin, Wei-Jye, Jiang, Cheng, Salton, Stephen R., Newgard, Christopher B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5624795/
https://ncbi.nlm.nih.gov/pubmed/28877479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.08.050
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