A HIGH THROUGHPUT MASS SPECTROMETRIC ASSAY FOR DISCOVERY OF HUMAN LIPOXYGENASE INHIBITORS AND ALLOSTERIC EFFECTORS

Lipoxygenases (LOX) regulate inflammation through the production of a variety of molecules whose specific downstream effects are not entirely understood due to the complexity of the inflammation pathway. The generation of these biomolecules can potentially be inhibited and/or allosterically regulate...

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Bibliographic Details
Published in:Anal Biochem
Main Authors: Jameson, J. Brian, Kenyon, Victor, Holman, Theodore R.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398643/
https://ncbi.nlm.nih.gov/pubmed/25712042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2015.02.011
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