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Discovery of Platelet-Type 12-Human Lipoxygenase Selective Inhibitors by High-Throughput Screening of Structurally Diverse Libraries

Human lipoxygenases (hLO) have been implicated in a variety of diseases and cancers and each hLO isozyme appears to have distinct roles in cellular biology. This fact emphasizes the need for discovering selective hLO inhibitors for both understanding the role of specific lipoxygenases in the cell an...

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Hlavní autoři: Deschamps, Joshua D., Gautschi, Jeffrey T., Whitman, Stephanie, Johnson, Tyler A., Gassner, Nadine C., Crews, Phillip, Holman, Theodore R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2203963/
https://ncbi.nlm.nih.gov/pubmed/17826100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2007.08.015
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