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(13)C NMR detects conformational change in the 100-kD membrane transporter ClC-ec1
CLC transporters catalyze the exchange of Cl(-) for H(+) across cellular membranes. To do so, they must couple Cl(-) and H(+) binding and unbinding to protein conformational change. However, the sole conformational changes distinguished crystallographically are small movements of a glutamate side ch...
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| Publicado no: | J Biomol NMR |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4398623/ https://ncbi.nlm.nih.gov/pubmed/25631353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-015-9898-7 |
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