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Substrate-driven conformational changes in ClC-ec1 observed by fluorine NMR
The CLC ‘Cl(−) channel' family consists of both Cl(−)/H(+) antiporters and Cl(−) channels. Although CLC channels can undergo large, conformational changes involving cooperativity between the two protein subunits, it has been hypothesized that conformational changes in the antiporters may be lim...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2771095/ https://ncbi.nlm.nih.gov/pubmed/19745816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.259 |
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