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Molecular Basis for Differential Anion Binding and Proton Coupling in the Cl(−)/H(+) Exchanger ClC-ec1
Cl(−)/H(+) transporters of the CLC superfamily form a ubiquitous class of membrane proteins that catalyze stoichiometrically coupled exchange of Cl(−) and H(+) across biological membranes. CLC transporters exchange H(+) for halides and certain polyatomic anions, but exclude cations, F(−), and larger...
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| Publicado no: | J Am Chem Soc |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4898471/ https://ncbi.nlm.nih.gov/pubmed/26880377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b12062 |
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