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Phospho-Tyrosine(s) vs. Phosphatidylinositol Binding in Shc Mediated Integrin Signaling
The Shc adaptor protein, particularly its p52 isoform, has been identified as a primary signaling partner for the tyrosine(s)-phosphorylated cytoplasmic tails of activated β(3) integrins. Inspired by our recent structure of the Shc PTB domain in complex with a bi-phosphorylated peptide derived from...
Tallennettuna:
| Julkaisussa: | Am J Mol Biol |
|---|---|
| Päätekijät: | , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2015
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4397963/ https://ncbi.nlm.nih.gov/pubmed/25893141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4236/ajmb.2015.52003 |
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