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Integrin-mediated Tyrosine Phosphorylation of Shc in T Cells Is Regulated by Protein Kinase C-dependent Phosphorylations of Lck

Integrin receptor signals are costimulatory for mitogenesis with the T-cell receptor during T-cell activation. A subset of integrin receptors can link to the adapter protein Shc and provide a mitogenic stimulus. Using a combination of genetic and pharmacological approaches, we show herein that integ...

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Detalhes bibliográficos
Main Authors: Niu, Shi, Xie, Haichun, Marcantonio, Eugene E.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC149976/
https://ncbi.nlm.nih.gov/pubmed/12589038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-07-0382
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