Radioprotection of the Brain White Matter by Mn(III) N-Butoxyethylpyridylporphyrin-Based Superoxide Dismutase Mimic MnTnBuOE-2-PyP(5+)

Cranial irradiation is a standard therapy for primary and metastatic brain tumors. A major drawback of radiotherapy (RT), however, is long-term cognitive loss that affects quality of life. Radiation-induced oxidative stress in normal brain tissue is thought to contribute to cognitive decline. We eva...

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Publicado en:Mol Cancer Ther
Main Authors: Weitzel, Douglas H., Tovmasyan, Artak, Ashcraft, Kathleen A., Rajic, Zrinka, Weitner, Tin, Liu, Chunlei, Li, Wei, Buckley, Anne F., Prasad, Mark R., Young, Kenneth H., Rodriguiz, Ramona M., Wetsel, William C., Peters, Katherine B., Spasojevic, Ivan, Herndon, James E., Batinic-Haberle, Ines, Dewhirst, Mark W.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397941/
https://ncbi.nlm.nih.gov/pubmed/25319393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-14-0343
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