Estradiol Promotes Sudden Cardiac Death in Transgenic Long-QT Type 2 Rabbits while Progesterone is Protective

BACKGROUND AND OBJECTIVE: Postpubertal women with inherited long-QT syndrome 2 (LQT2) are at increased risk for polymorphic ventricular tachycardia (pVT) and sudden cardiac death (SCD), particularly during the postpartum. We aimed at investigating whether sex hormones directly modulate the arrhythmo...

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Détails bibliographiques
Publié dans:Heart Rhythm
Auteurs principaux: Odening, Katja E., Choi, Bum-Rak, Liu, Gong Xin, Hartmann, Kathryn, Ziv, Ohad, Chaves, Leonard, Schofield, Lorraine, Centracchio, Jason, Zehender, Manfred, Peng, Xuwen, Brunner, Michael, Koren, Gideon
Format: Artigo
Langue:Inglês
Publié: 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397932/
https://ncbi.nlm.nih.gov/pubmed/22245795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2012.01.009
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