Non-Aggregating Tau Phosphorylation by Cyclin-Dependent Kinase 5 Contributes to Motor Neuron Degeneration in Spinal Muscular Atrophy

Mechanisms underlying motor neuron degeneration in spinal muscular atrophy (SMA), the leading inherited cause of infant mortality, remain largely unknown. Many studies have established the importance of hyperphosphorylation of the microtubule-associated protein tau in various neurodegenerative disor...

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Publicado en:J Neurosci
Autores principales: Miller, Nimrod, Feng, Zhihua, Edens, Brittany M., Yang, Ben, Shi, Han, Sze, Christie C., Hong, Benjamin Taige, Su, Susan C., Cantu, Jorge A., Topczewski, Jacek, Crawford, Thomas O., Ko, Chien-Ping, Sumner, Charlotte J., Ma, Long, Ma, Yong-Chao
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2015
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397602/
https://ncbi.nlm.nih.gov/pubmed/25878277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3716-14.2015
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