Non-Aggregating Tau Phosphorylation by Cyclin-Dependent Kinase 5 Contributes to Motor Neuron Degeneration in Spinal Muscular Atrophy

Mechanisms underlying motor neuron degeneration in spinal muscular atrophy (SMA), the leading inherited cause of infant mortality, remain largely unknown. Many studies have established the importance of hyperphosphorylation of the microtubule-associated protein tau in various neurodegenerative disor...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Miller, Nimrod, Feng, Zhihua, Edens, Brittany M., Yang, Ben, Shi, Han, Sze, Christie C., Hong, Benjamin Taige, Su, Susan C., Cantu, Jorge A., Topczewski, Jacek, Crawford, Thomas O., Ko, Chien-Ping, Sumner, Charlotte J., Ma, Long, Ma, Yong-Chao
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397602/
https://ncbi.nlm.nih.gov/pubmed/25878277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3716-14.2015
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