Non-Aggregating Tau Phosphorylation by Cyclin-Dependent Kinase 5 Contributes to Motor Neuron Degeneration in Spinal Muscular Atrophy

Mechanisms underlying motor neuron degeneration in spinal muscular atrophy (SMA), the leading inherited cause of infant mortality, remain largely unknown. Many studies have established the importance of hyperphosphorylation of the microtubule-associated protein tau in various neurodegenerative disor...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Miller, Nimrod, Feng, Zhihua, Edens, Brittany M., Yang, Ben, Shi, Han, Sze, Christie C., Hong, Benjamin Taige, Su, Susan C., Cantu, Jorge A., Topczewski, Jacek, Crawford, Thomas O., Ko, Chien-Ping, Sumner, Charlotte J., Ma, Long, Ma, Yong-Chao
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2015
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397602/
https://ncbi.nlm.nih.gov/pubmed/25878277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3716-14.2015
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