Presynaptic C-terminal truncated tau is released from cortical synapses in Alzheimer's disease

The microtubule-associated protein tau has primarily been associated with axonal location and function; however, recent work shows tau release from neurons and suggests an important role for tau in synaptic plasticity. In our study, we measured synaptic levels of total tau using synaptosomes prepare...

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Bibliografiske detaljer
Udgivet i:J Neurochem
Main Authors: Sokolow, Sophie, Henkins, Kristen M., Bilousova, Tina, Gonzalez, Bianca, Vinters, Harry V., Miller, Carol A., Cornwell, Lindsey, Poon, Wayne W., Gylys, Karen H.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397171/
https://ncbi.nlm.nih.gov/pubmed/25393609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12991
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