Severe myopathy in mice lacking the MEF2/SRF-dependent gene leiomodin-3

Maintenance of skeletal muscle structure and function requires a precise stoichiometry of sarcomeric proteins for proper assembly of the contractile apparatus. Absence of components of the sarcomeric thin filaments causes nemaline myopathy, a lethal congenital muscle disorder associated with aberran...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Cenik, Bercin K., Garg, Ankit, McAnally, John R., Shelton, John M., Richardson, James A., Bassel-Duby, Rhonda, Olson, Eric N., Liu, Ning
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396495/
https://ncbi.nlm.nih.gov/pubmed/25774500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI80115
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