A myocardin-adjacent lncRNA balances SRF-dependent gene transcription in the heart

Myocardin, a potent coactivator of serum response factor (SRF), competes with ternary complex factor (TCF) proteins for SRF binding to balance opposing mitogenic and myogenic gene programs in cardiac and smooth muscle. Here we identify a cardiac lncRNA transcribed adjacent to myocardin, named CARDIN...

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Publicat a:Genes Dev
Autors principals: Anderson, Douglas M., Anderson, Kelly M., Nelson, Benjamin R., McAnally, John R., Bezprozvannaya, Svetlana, Shelton, John M., Bassel-Duby, Rhonda, Olson, Eric N.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2021
Matèries:
Research Communication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168554/
https://ncbi.nlm.nih.gov/pubmed/33985971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.348304.121
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