A myocardin-adjacent lncRNA balances SRF-dependent gene transcription in the heart

Myocardin, a potent coactivator of serum response factor (SRF), competes with ternary complex factor (TCF) proteins for SRF binding to balance opposing mitogenic and myogenic gene programs in cardiac and smooth muscle. Here we identify a cardiac lncRNA transcribed adjacent to myocardin, named CARDIN...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Anderson, Douglas M., Anderson, Kelly M., Nelson, Benjamin R., McAnally, John R., Bezprozvannaya, Svetlana, Shelton, John M., Bassel-Duby, Rhonda, Olson, Eric N.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2021
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168554/
https://ncbi.nlm.nih.gov/pubmed/33985971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.348304.121
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