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Severe myopathy in mice lacking the MEF2/SRF-dependent gene leiomodin-3
Maintenance of skeletal muscle structure and function requires a precise stoichiometry of sarcomeric proteins for proper assembly of the contractile apparatus. Absence of components of the sarcomeric thin filaments causes nemaline myopathy, a lethal congenital muscle disorder associated with aberran...
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| Publicado en: | J Clin Invest |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4396495/ https://ncbi.nlm.nih.gov/pubmed/25774500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI80115 |
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