Local mechanisms for loud sound-enhanced aminoglycoside entry into outer hair cells

Loud sound exposure exacerbates aminoglycoside ototoxicity, increasing the risk of permanent hearing loss and degrading the quality of life in affected individuals. We previously reported that loud sound exposure induces temporary threshold shifts (TTS) and enhances uptake of aminoglycosides, like g...

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Bibliographic Details
Published in:Front Cell Neurosci
Main Authors: Li, Hongzhe, Kachelmeier, Allan, Furness, David N., Steyger, Peter S.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2015
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396448/
https://ncbi.nlm.nih.gov/pubmed/25926770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00130
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