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Local mechanisms for loud sound-enhanced aminoglycoside entry into outer hair cells

Loud sound exposure exacerbates aminoglycoside ototoxicity, increasing the risk of permanent hearing loss and degrading the quality of life in affected individuals. We previously reported that loud sound exposure induces temporary threshold shifts (TTS) and enhances uptake of aminoglycosides, like g...

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Détails bibliographiques
Publié dans:Front Cell Neurosci
Auteurs principaux: Li, Hongzhe, Kachelmeier, Allan, Furness, David N., Steyger, Peter S.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396448/
https://ncbi.nlm.nih.gov/pubmed/25926770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00130
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