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TRPA1-Mediated Accumulation of Aminoglycosides in Mouse Cochlear Outer Hair Cells

Aminoglycoside ototoxicity involves the accumulation of antibiotic molecules in the inner ear hair cells and the subsequent degeneration of these cells. The exact route of entry of aminoglycosides into the hair cells in vivo is still unknown. Similar to other small organic cations, aminoglycosides c...

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Detalhes bibliográficos
Main Authors: Stepanyan, Ruben S., Indzhykulian, Artur A., Vélez-Ortega, A. Catalina, Boger, Erich T., Steyger, Peter S., Friedman, Thomas B., Frolenkov, Gregory I.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214240/
https://ncbi.nlm.nih.gov/pubmed/21879401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10162-011-0288-x
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