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Fast Adaptation and Ca(2+) Sensitivity of the Mechanotransducer Require Myosin-XVa in Inner But Not Outer Cochlear Hair Cells

In inner ear hair cells, activation of mechanotransduction channels is followed by extremely rapid deactivation that depends on the influx of Ca(2+) through these channels. Although the molecular mechanisms of this “fast” adaptation are largely unknown, the predominant models assume Ca(2+) sensitivi...

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Hlavní autoři: Stepanyan, Ruben, Frolenkov, Gregory I.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702482/
https://ncbi.nlm.nih.gov/pubmed/19339598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4566-08.2009
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