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Fast Adaptation and Ca(2+) Sensitivity of the Mechanotransducer Require Myosin-XVa in Inner But Not Outer Cochlear Hair Cells

In inner ear hair cells, activation of mechanotransduction channels is followed by extremely rapid deactivation that depends on the influx of Ca(2+) through these channels. Although the molecular mechanisms of this “fast” adaptation are largely unknown, the predominant models assume Ca(2+) sensitivi...

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Bibliografske podrobnosti
Main Authors: Stepanyan, Ruben, Frolenkov, Gregory I.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702482/
https://ncbi.nlm.nih.gov/pubmed/19339598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4566-08.2009
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