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Local mechanisms for loud sound-enhanced aminoglycoside entry into outer hair cells

Loud sound exposure exacerbates aminoglycoside ototoxicity, increasing the risk of permanent hearing loss and degrading the quality of life in affected individuals. We previously reported that loud sound exposure induces temporary threshold shifts (TTS) and enhances uptake of aminoglycosides, like g...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Li, Hongzhe, Kachelmeier, Allan, Furness, David N., Steyger, Peter S.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396448/
https://ncbi.nlm.nih.gov/pubmed/25926770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00130
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