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Predicting response to multidrug regimens in cancer patients using cell line experiments and regularised regression models

BACKGROUND: Patients suffering from cancer are often treated with a range of chemotherapeutic agents, but the treatment efficacy varies greatly between patients. Based on recent popularisation of regularised regression models the goal of this study was to establish workflows for pharmacogenomic pred...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Falgreen, Steffen, Dybkær, Karen, Young, Ken H, Xu-Monette, Zijun Y, El-Galaly, Tarec C, Laursen, Maria Bach, Bødker, Julie S, Kjeldsen, Malene K, Schmitz, Alexander, Nyegaard, Mette, Johnsen, Hans Erik, Bøgsted, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396063/
https://ncbi.nlm.nih.gov/pubmed/25881228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1237-6
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