Exposure time independent summary statistics for assessment of drug dependent cell line growth inhibition

BACKGROUND: In vitro generated dose-response curves of human cancer cell lines are widely used to develop new therapeutics. The curves are summarised by simplified statistics that ignore the conventionally used dose-response curves’ dependency on drug exposure time and growth kinetics. This may lead...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Falgreen, Steffen, Laursen, Maria Bach, Bødker, Julie Støve, Kjeldsen, Malene Krag, Schmitz, Alexander, Nyegaard, Mette, Johnsen, Hans Erik, Dybkær, Karen, Bøgsted, Martin
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Methodology Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4127655/
https://ncbi.nlm.nih.gov/pubmed/24902483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-15-168
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker