Predicting response to multidrug regimens in cancer patients using cell line experiments and regularised regression models

BACKGROUND: Patients suffering from cancer are often treated with a range of chemotherapeutic agents, but the treatment efficacy varies greatly between patients. Based on recent popularisation of regularised regression models the goal of this study was to establish workflows for pharmacogenomic pred...

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Vydáno v:BMC Cancer
Hlavní autoři: Falgreen, Steffen, Dybkær, Karen, Young, Ken H, Xu-Monette, Zijun Y, El-Galaly, Tarec C, Laursen, Maria Bach, Bødker, Julie S, Kjeldsen, Malene K, Schmitz, Alexander, Nyegaard, Mette, Johnsen, Hans Erik, Bøgsted, Martin
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396063/
https://ncbi.nlm.nih.gov/pubmed/25881228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1237-6
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