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Nutritional Energy Stimulates NAD(+) Production to Promote Tankyrase-Mediated PARsylation in Insulinoma Cells
The poly-ADP-ribosylation (PARsylation) activity of tankyrase (TNKS) regulates diverse physiological processes including energy metabolism and wnt/β-catenin signaling. This TNKS activity uses NAD(+) as a co-substrate to post-translationally modify various acceptor proteins including TNKS itself. PAR...
שמור ב:
| הוצא לאור ב: | PLoS One |
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| Main Authors: | , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Public Library of Science
2015
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4395342/ https://ncbi.nlm.nih.gov/pubmed/25876076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122948 |
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