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Insulin-stimulated exocytosis of GLUT4 is enhanced by IRAP and its partner tankyrase

The glucose transporter GLUT4 and the aminopeptidase IRAP (insulin-responsive aminopeptidase) are the major cargo proteins of GSVs (GLUT4 storage vesicles) in adipocytes and myocytes. In the basal state, most GSVs are sequestered in perinuclear and other cytosolic compartments. Following insulin sti...

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Detalhes bibliográficos
Main Authors: Yeh, Tsung-Yin J., Sbodio, Juan I., Tsun, Zhi-Yang, Luo, Biao, Chi, Nai-Wen
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1798437/
https://ncbi.nlm.nih.gov/pubmed/17059388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060793
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