Nutritional Energy Stimulates NAD(+) Production to Promote Tankyrase-Mediated PARsylation in Insulinoma Cells

The poly-ADP-ribosylation (PARsylation) activity of tankyrase (TNKS) regulates diverse physiological processes including energy metabolism and wnt/β-catenin signaling. This TNKS activity uses NAD(+) as a co-substrate to post-translationally modify various acceptor proteins including TNKS itself. PAR...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Zhong, Linlin, Yeh, Tsung-Yin J., Hao, Jun, Pourtabatabaei, Nasim, Mahata, Sushil K., Shao, Jianhua, Chessler, Steven D., Chi, Nai-Wen
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4395342/
https://ncbi.nlm.nih.gov/pubmed/25876076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122948
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki