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Hypermetabolism, Hyperphagia, and Reduced Adiposity in Tankyrase-Deficient Mice
OBJECTIVE: Tankyrase (TNKS) is a Golgi-associated poly-ADP-ribose polymerase that is implicated in the regulation of GLUT4 trafficking in 3T3-L1 adipocytes. Its chromosomal locus 8p23.1 is linked to monogenic forms of diabetes in certain kindred. We hypothesize that TNKS is involved in energy homeos...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Diabetes Association
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2768175/ https://ncbi.nlm.nih.gov/pubmed/19651815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-1781 |
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