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Mitotic entry in the presence of DNA damage is a widespread property of aneuploidy in yeast

Genetic instability is a hallmark of aneuploidy in budding and fission yeast. All aneuploid yeast strains analyzed to date harbor elevated levels of Rad52-GFP foci, a sign of DNA damage. Here we investigate how continuously elevated levels of DNA damage affect aneuploid cells. We show that Rad52-GFP...

詳細記述

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書誌詳細
出版年:Mol Biol Cell
主要な著者: Blank, Heidi M., Sheltzer, Jason M., Meehl, Colleen M., Amon, Angelika
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Cell Biology 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4395125/
https://ncbi.nlm.nih.gov/pubmed/25694455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-10-1442
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