Metformin Inhibits Growth of Human Glioblastoma Cells and Enhances Therapeutic Response

High-grade gliomas, glioblastomas (GB), are refractory to conventional treatment combining surgery, chemotherapy, mainly temozolomide, and radiotherapy. This highlights an urgent need to develop novel therapies and increase the efficacy of radio/chemotherapy for these very aggressive and malignant b...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sesen, Julie, Dahan, Perrine, Scotland, Sarah J., Saland, Estelle, Dang, Van-Thi, Lemarié, Anthony, Tyler, Betty M., Brem, Henry, Toulas, Christine, Cohen-Jonathan Moyal, Elizabeth, Sarry, Jean-Emmanuel, Skuli, Nicolas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4395104/
https://ncbi.nlm.nih.gov/pubmed/25867026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123721
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