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Inhibition of Akt inhibits growth of glioblastoma and glioblastoma stem-like cells
A commonly activated signaling cascade in many human malignancies including glioblastoma multiforme (GBM) is the Akt pathway. This pathway can be activated via numerous upstream alterations including genomic amplification of EGFR, PTEN deletion, or PIK3CA mutations. In this study, we screened PI3K/A...
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| Publicado no: | Mol Cancer Ther |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4498795/ https://ncbi.nlm.nih.gov/pubmed/19208828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-08-0680 |
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