Metformin Inhibits Growth of Human Glioblastoma Cells and Enhances Therapeutic Response

High-grade gliomas, glioblastomas (GB), are refractory to conventional treatment combining surgery, chemotherapy, mainly temozolomide, and radiotherapy. This highlights an urgent need to develop novel therapies and increase the efficacy of radio/chemotherapy for these very aggressive and malignant b...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Sesen, Julie, Dahan, Perrine, Scotland, Sarah J., Saland, Estelle, Dang, Van-Thi, Lemarié, Anthony, Tyler, Betty M., Brem, Henry, Toulas, Christine, Cohen-Jonathan Moyal, Elizabeth, Sarry, Jean-Emmanuel, Skuli, Nicolas
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4395104/
https://ncbi.nlm.nih.gov/pubmed/25867026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123721
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