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Eravacycline (TP-434) Is Efficacious in Animal Models of Infection

Eravacycline is a novel broad-spectrum fluorocycline antibiotic being developed for a wide range of serious infections. Eravacycline was efficacious in mouse septicemia models, demonstrating 50% protective dose (PD(50)) values of ≤1 mg/kg of body weight once a day (q.d.) against Staphylococcus aureu...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Grossman, Trudy H., Murphy, Timothy M., Slee, Andrew M., Lofland, Denene, Sutcliffe, Joyce A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394802/
https://ncbi.nlm.nih.gov/pubmed/25691636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04354-14
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