The Fluorocycline TP-271 Is Efficacious in Models of Aerosolized Francisella tularensis SCHU S4 Infection in BALB/c Mice and Cynomolgus Macaques

TP-271 is a novel, fully synthetic fluorocycline in development for complicated bacterial respiratory infections. TP-271 was active in vitro against a panel of 29 Francisella tularensis isolates, showing MICs against 50% and 90% of isolates of 0.25 and 0.5 μg/ml, respectively. In a mouse model of in...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Antimicrob Agents Chemother
Egile Nagusiak: Grossman, Trudy H., Anderson, Michael S., Christ, David, Gooldy, Melanie, Henning, Lisa N., Heine, Henry S., Kindt, M. Victoria, Lin, Winston, Siefkas-Patterson, Kaylyn, Radcliff, Anne K., Tam, Vincent H., Sutcliffe, Joyce A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2017
Gaiak:
Pharmacology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527625/
https://ncbi.nlm.nih.gov/pubmed/28559261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00448-17
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak