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Target- and Resistance-Based Mechanistic Studies with TP-434, a Novel Fluorocycline Antibiotic
TP-434 is a novel, broad-spectrum fluorocycline antibiotic with activity against bacteria expressing major antibiotic resistance mechanisms, including tetracycline-specific efflux and ribosomal protection. The mechanism of action of TP-434 was assessed using both cell-based and in vitro assays. In E...
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| Main Authors: | , , , , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
American Society for Microbiology
2012
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3346605/ https://ncbi.nlm.nih.gov/pubmed/22354310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.06187-11 |
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