Polymyxin Resistance Caused by mgrB Inactivation Is Not Associated with Significant Biological Cost in Klebsiella pneumoniae

The inactivation of the mgrB gene, which encodes a negative-feedback regulator of the PhoPQ signaling system, was recently shown to be a common mutational mechanism responsible for acquired polymyxin resistance among carbapenemase-producing Klebsiella pneumoniae strains from clinical sources. In thi...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Antimicrob Agents Chemother
Main Authors: Cannatelli, Antonio, Santos-Lopez, Alfonso, Giani, Tommaso, Gonzalez-Zorn, Bruno, Rossolini, Gian Maria
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2015
נושאים:
Mechanisms of Resistance
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394794/
https://ncbi.nlm.nih.gov/pubmed/25691629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04998-14
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