mgrB Mutations Mediating Polymyxin B Resistance in Klebsiella pneumoniae Isolates from Rectal Surveillance Swabs in Brazil

We aimed to investigate polymyxin B (PMB) resistance and its molecular mechanisms in 126 Klebsiella pneumoniae isolates from rectal swabs in Brazil. Ten isolates exhibited PMB resistance with interruption of mgrB gene by insertion sequences or missense mutations. Most of the PMB-resistant isolates h...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Aires, Caio Augusto Martins, Pereira, Polyana Silva, Asensi, Marise Dutra, Carvalho-Assef, Ana Paula D'Alincourt
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2016
Fag:
Mechanisms of Resistance
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075120/
https://ncbi.nlm.nih.gov/pubmed/27620478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01456-16
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