mgrB Mutations Mediating Polymyxin B Resistance in Klebsiella pneumoniae Isolates from Rectal Surveillance Swabs in Brazil

We aimed to investigate polymyxin B (PMB) resistance and its molecular mechanisms in 126 Klebsiella pneumoniae isolates from rectal swabs in Brazil. Ten isolates exhibited PMB resistance with interruption of mgrB gene by insertion sequences or missense mutations. Most of the PMB-resistant isolates h...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Aires, Caio Augusto Martins, Pereira, Polyana Silva, Asensi, Marise Dutra, Carvalho-Assef, Ana Paula D'Alincourt
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
Mechanisms of Resistance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075120/
https://ncbi.nlm.nih.gov/pubmed/27620478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01456-16
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