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Chemical Inhibition of Bacterial Ribosome Biogenesis Shows Efficacy in a Worm Infection Model
The development of antibacterial compounds that perturb novel processes is an imperative in the challenge presented by widespread antibiotic resistance. While many antibiotics target the ribosome, molecules that inhibit ribosome assembly have yet to be used in this manner. Here we show that a novel...
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| Veröffentlicht in: | Antimicrob Agents Chemother |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4394774/ https://ncbi.nlm.nih.gov/pubmed/25712357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04690-14 |
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